Our Clients

Advanced BioHealing, Inc. is a biomedical company commercializing products based on its proprietary cell culture and tissue preservation technologies. Celaderm™, the Company's lead product, represents a significant step forward in advanced wound care technology: it is the first clinically effective cell-based wound dressing that is inexpensive to produce and capable of being stored in a conventional freezer ready for immediate use. Advanced BioHealing was acquired for $750M in cash by Shire Pharmaceuticals in July 2011 as the base on which to build Shire's regenerative medicine business.

Lerner Medical Devices, Inc. has developed a proprietary medical device to treat scalp psoriasis, a widespread chronic skin disease affecting approximately 3.8 million people in the U.S. and over 7.5 million globally. The High Intensity Fiber Optic Light (HIFOL) LiteBrush™ delivers therapeutic light through optical fibers, offering decisively superior results over any other trea™ent modality on the market today, including pills, injectables or topicals, with minimal side effects and lower overall cost. The LiteBrush™ system is FDA cleared and patented.

Core Essence Orthopaedics creates innovative products that help perfect high-volume, sports medicine procedures involving soft tissue and skeletal repair of the extremities. The company's products better enable surgeons to perform minimally invasive arthroscopic and endoscopic procedures, leading to higher success rates and lower recovery times.

The intuitive product portfolio of Core Essence Orthopaedics is utilized by hospitals and surgery centers across the nation.

MedAvante's Centralized Expert Ratings Services is a unique service based on the recognition that psychological assessments are the most important component of the clinical trial for mental illness therapeutics, establishing the foundation upon which the study rests. MedAvante's approach improves signal detection for CNS trials by centralizing psychometric assessments in the hands of fewer expert rates via high resolution video-conferencing and telephone. Centralizing the assessments increases the accuracy, reliability and quality of the psychiatric diagonstic and symptom assessments. This can:

• Reduce variability by reducing the sheer number of raters required for a study.
• Reduce inappropriate patient enrollment due to misaligned incentives, because the raters are not associated with the investigative site.
• Reduce expectancy bias because remote assessors can be blinded to study protocols and visit sequence.
• Improve inter-rater reliability and interview quality by using highly trained and finely calibrated expert raters.
• Overall, reducing inter-rater variability increases a study's power to detect a difference between the drug and the placebo.

The net effect:

MedAvante's Centralized Expert Ratings Services provide pharmaceutical companies with faster, more certain decision making regarding CNS drugs.

Pharmacopeia Drug Discovery, Inc. is a publicly traded (NASDAQ: PCOP) chemistry-based collaborative drug discovery company, focused on the creation of small molecule therapeutics

PTC Therapeutics, Inc. is a biopharmaceutical company focused on the discovery, development, and commercialization of small-molecule drugs targeting post-transcriptional control mechanisms

QuantumBio, Inc is accelerating the drug discovery efforts by providing pharmaceutical, biotechnology companies and life science research organizations a next generation of Computer-Assisted Molecular Modeling (CAMM) and Computer-Assisted Drug Design (CADD) solutions

WuXi PharmaTech is a contract chemistry research and product development services company located in the WaiGaoQiao Free Trade Zone of Shanghai. Founded by a veteran of the US biotechnology industry, WuXi PharmaTech provides customers access to cost-effective world-class medicinal chemistry from a state-of-the-art research chemistry laboratory in Shanghai. The company's current customers include fourteen of the world's twenty largest pharmaceutical companies as well as dozens of prominent biotech companies. WuXi PharmaTech's laboratories are equipped with state-of-the-art instrumentation operated by experienced scientists to ensure high throughput synthesis combined with tight quality control and precise analysis. The company conducts custom synthesis, process research, scale up services and bulk synthesis of pharmaceutical intermediates

Azure Therapeutics is a seed stage that has developed a proprietary topical non-antihistamine, non-steroidal product for the relief of chronic itch.